"Some scientists say the rise is linked to use of weapons containing depleted uranium (DU) by the US-led coalition that invaded the country in 2001.
A Canadian research group found very high levels of uranium in Afghans during tests just after the invasion.
A US forces spokesman denied its weapons were affecting the health of Afghans or the country's environment.
But claims made in the BBC World Service One Planet programme suggest the invasion may have left an unwelcome legacy for the country's environment and the health of its people.
Doctors in Kabul and Kandahar showed data indicating that the incidence of a number of health conditions, including birth defects, has doubled in under two years."
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